Searchable abstracts of presentations at key conferences on calcified tissues

ba0003pp257 | Osteoporosis: pathophysiology and epidemiology | ECTS2014

Molecular evidence of osteoblast dysfunction in elderly men with osteoporotic hip fractures

Foger-Samwald Ursula , Afarin Alaghebandan , Patsch Janina , Schamall Doris , Salem Sylvia , Mousavi Mehdi , Pietschmann Peter

Fractures of the hip are serious complications associated with osteoporosis. In previous work we found evidence of osteoblast dysfunction in middle aged men with idiopathic osteoporosis. The aim of this study was to investigate gene expression and bone microarchitecture in bone samples derived from elderly men with osteoporotic hip fractures. Femoral heads and adjacent bone tissue from 12 men with low-trauma hip fractures (mean age 82±7 years) and consecutive surgical hip...